Since my first year of university, I wanted to understand the mechanisms linked to antimicrobial resistance. Thus, I aimed to contribute my efforts to the fight against the rise of multi-resistant bacteria by characterizing novel resistance determinants among Gram-negative pathogens. I have been working during my PhD on both enzyme-mediated carbapenem and colistin resistance by identifying the origin of their corresponding genes and by characterizing their mobilization mechanisms into clinical isolates with Prof. Patrice Nordmann and Dr. Laurent Poirel at the University of Fribourg, Switzerland. In my first postdoc position, I participated in the characterization of new fosfomycin resistance genes and in the elaboration of new rapid diagnostic tools to detect resistant isolates. During my second postdoc at the University of Gothenburg in Sweden with Prof. Joakim Larsson, I studied the emergence of new integron-borne resistance cassettes using functional metagenomics from complex environmental samples.

At the end of 2021, I joined the MBA lab where I will focus deeper in the characterization of integron gene cassettes of unknown functions that are located in mobile integrons and could potentially represent unidentified new resistance mechanisms.