December 2017

19 dic 2017 - 10:28 CET

Juan Luis Paris successfully defended his PhD thesis entitled "Ultrasound-Responsive Mesoporous Silica Nanoparticles for Biomedical Applications"

In this thesis, different approaches to drug delivery systems were studied:

 ​- ​Drug release induced by ultrasound through mesoporous silica nanoparticles coated with thermo- and ultrasound-sensitive polymers.

 ​- ​ Ultrasound-enhanced nanoparticle uptake by cancer cells through the removal of a polyethylene glycol shield anchored to mesoporous silica nanoparticles.

 ​ - ​ Cavitation-enhanced accumulation and penetration of nanoparticles in tumor tissue by combining mesoporous silica nanoparticles with gas-stabilizing polymeric particles.

 - ​ Cellular transport of mesoporous silica nanoparticles towards tumors employing placental mesenchymal stem cells as carriers of the nanoparticles.