Grupos de investigación

Members

Ignacio Lizasoain is currently Full Professor in the Department of Pharmacology and Toxicology at the School of Medicine of Universidad Complutense in Madrid (UCM, Spain). Ignacio Lizasoain graduated from Complutense Medical School in 1986, obtained his Medical Doctor in 1986 and his PhD in Medicine in 1992 (Extraordinary prize). He has 6 recognized “six-year research” periods (5 of research and 1 of transfer of knowledge; being the latest ones "active").

He had positions such as FPI and Marie Curie fellow, Aggregate, Lecturer, Associate and, since 2007, as Full Professor. As a postdoctoral, he worked in Wellcome Foundation LTD (Beckenham, UK) with Prof. Salvador Moncada from 1991 to 1994 and in Massachusetts General Hospital (Harvard Medical School, Boston, USA) with Prof. Eng H Lo in 2010. He was External Examiner of the Trinity College of Dublin (School of Pharmacy and Pharmaceutical Sciences, University of Dublin, Ireland) from 2008 to 2010.

Dr. Lizasoain also co-leads the Neurovascular Diseases Group at Hospital Health Institute "12 de Octubre” (i+12). He coordinates the Spanish Neurovascular Network (RICORS-ICTUS) and participates in the Consortium International pour la Recherche Circadienne sur l’AVC (CIRCA).

In the Complutense University, he has held management positions such as Chair of Department Pharmacology at Complutense Medical School (2006-2010), Academic Secretary of Department Pharmacology (2010-2015), Coordinator Campus of Excellence Moncloa (2010) and Vice-Provost of Research and Doctoral Studies at Complutense University (2015-2019).

He has published extensively in the area of neuroscience and neurological sciences especially in the neurovascular research field (stroke). His scientific production includes more than 175 JCR and PubMed papers with more than 12.000-17.000 total citations and “h-index” of 60/71 (Scopus/Google scholar, November-2022). The complete list of publications can be found at Scopus, Orcid and Google Scholar. He is included among the best Spanish scientists and is among the Top 2% of World Scientists according to AD Scientific Index


Jesus Pradillo is graduated in Biology (UCM, 2000) and he obtained his PhD in Sciences in 2008 (Extraordinary Prize). He has completed several national and international stays, highlighting a predoctoral stay at the School of Pharmacy of Trinity College, Dublin, Ireland in 2006 and a postdoctoral stay in the Neuroinflammation Group at the University of Manchester, UK (2009-2013).

He obtained a position as Lecturer in the Department of Psychobiology at the School of Psychology of the UCM in 2017 and he is currently a Lecturer in the Department of Pharmacology and Toxicology at the School of Medicine at UCM.

As a researcher, Jesus has studied different aspects within the physiopathology of stroke. His scientific production includes 39 JCR and PubMed papers with more than 1.700 total citations and “h-index” of 22 (Scopus, December-2019). The complete list of publications can be found at Scopus and Orcid.


Ana Moraga is graduated in Biology (Universidad de Granada) and she obtained her PhD in Biomedicine in 2014 at UCM as an FPI fellow. She has completed several international stays, highlighting a predoctoral stay in 2012 at the Weill Cornell Medical College (New York, USA) under the supervision of Prof. Costantino Iadecola, and two postdoctoral stays at King’s College of London, UK (2015-2018) and at Queen Mary University of London, UK (2018-2020).

She obtained a position as a Lecturer in the Department of Cell Biology at the School of Medicine of the UCM in 2022. As a researcher, she is currently developing a project focused on the role of neutrophil extracellular traps (NETs) in stroke at Neurovascular Disease Group at Hospital Health Institute "12 de Octubre" (i+12) and UCM. Her scientific production includes 22 JCR and PubMed papers with more than 1000 total citations and “h-index” of 17 (Scopus). The complete list of publications can be found at Scopus and Orcid.


Macarena Hernández Jiménez is graduated in Biology by the Alcalá University of Madrid (UAH), PhD in Biomedicine in 2010 at UAH, MSc in Clinical Neuropsychology (ITEAP, 2017) and Expert in Pharmacovigilance (CEU, 2020). She completed a postdoctoral stay (2011-2017) at the Neurovascular Disease Group (12 de Octubre Hospital and UCM). Since 2017, she works as a Scientific Director in AptaTargets, a biopharmaceutical company focused on TLR4-mediated diseases treatment. She is currently Associate Professor at the Pharmacology and Toxicology Department at the Complutense Medical School. 

As a researcher, she is interested in therapeutic targets involved in the cerebral ischemia pathophysiology and the role of TLR4 in different diseases (stroke, myocardial infarction, multiple sclerosis and COVID-19), as well as the translation from animal studies to clinical investigation. She has directed two clinical trials in healthy volunteers and is the current director of two clinical trials to determine the effect of a TLR4 antagonist in stroke and in COVID-19 patients. The complete list of contributions can be found at ORCID: https://orcid.org/my-orcid?orcid=0000-0003-3329-3965 and at ClinicalTrials.gov: https://clinicaltrials.gov/ct2/results?cond=&term=ApTOLL&cntry=&state=&city=&dist=


Manuel Navarro-Oviedo graduated in Pharmacy (UCM, 2014) obtained his PhD in Applied Medicine and Biomedicine (2020) at the University of Navarra. He has completed a predoctoral stay (2019) and later a postdoctoral stay (2020-2022) at the UMR-S 1237 laboratory, Physiopathology and Imaging of Neurovascular Disorders (PhIND), headed by Dr. Denis Vivien, at the University of Caen (France), under the supervision of Dr. Maxime Gauberti and Sara Martinez de Lizarrondo.

During his predoctoral stage, he worked in the field different Neurovascular diseases as Intracranial Hemorrhage, Ischemic Stroke, and Intracranial Aneurysm. Additionally, during his postdoctoral stage, he worked on a molecular MRI tool, using Microparticles of Iron Oxide (MPIOs) as contrast agent, for the diagnosis of Neuroinflammatory diseases.

Currently, as a Margarita Salas postdoctoral researcher, he is working on a project developing an experimental model of Cerebral Vasculitis and studying the role of TLR-4 receptor. The complete list of publications can be found at ORCID:  https://orcid.org/0000-0003-2095-5501


Arturo González de la Aleja, graduated in Biochemistry (UCLM, 2015), obtained his PhD in Biochemistry and Molecular Biology as a FPU researcher (UCM-CSIC, 2022) on the role of nuclear receptors in human macrophage polarization. During his PhD he also completed a international stay in Münster (Germany).

He has been working the last years on the importance of nuclear receptors in monocyte and macrophage biology in homeostasis and pathology. As a postdoctoral researcher, he is interested in the molecular mechanisms that regulate the immune response after and before stroke.


Cristina Granados Martínez has a degree in Biology from the Autonomous University of Madrid (UAM, 2018), and in Neuroscience (MSc) from the Complutense University of Madrid (UCM, 2020).
She worked as a research assistant at the Neurovascular Research Unit of the Department of Pharmacology and Toxicology of the Faculty of Medicine of the Complutense (UCM), where she is currently a PhD student.