Pedro Antonio Reche Gallardo

Associate Professor of Immunology

Contact

Dr. Pedro Reche, PhD

Departamento de Microbiología I

Immunology Division, Office # 10

Facultad de Medicina

Universidad Complutense de Madrid

28040, Madrid, España

EM: parecheg at med . ucm . es

 acacia

LINKEDIN: https://www.linkedin.com/in/reche

GOOGLE SCHOLARS USER: Reche

RESEARCHGATE: Pedro_Reche

SCOPUS AUTHOR ID: 6603677069

ORCID: 0000-0003-3966-5838

Dr. Pedro Reche is s multidisplinary scientist with relevant contributions on the fields of Biochemistry, Molecular Biology, Bioinformatics and Immunology. Hes has published over 50 articles in peer review journals that have received more  than 3000 citations. He joined the Complutense University of Madrid in 2006 to lead the Immunomedicine Group. Dr. Reche"s group have a wide range of research interests but we are specially interested on  deciphering the factors that determine immunogenicity and the develpment of computer-assited epitope-based vaccines.


Education

  • 1995 – PhD in Chemistry, Bioquemistry. University of Granada, Granada, Spain

  • 1990 – Bachelor Degree in Chemistry. Faculty of Sciences, University of Granada, Spain.


Research Career

  • 06/2006–present. Immunomedicine Group Leader. Department of Microbiology I (Immunology), Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

    • Topic: Immunomedicine and Immunonformatics.

  • 07/2005–06/2006. Director of the Department of Bioinformatics of the Cancer Vaccine Center. Dana-Farber Institute, Harvard Medical School, Boston, MA, USA

    • Topic: Computational Immunology and Cancer Immunothrerapy.

    • Reporting to: Prof. Ellis L. Reinherz, Director

  • 03/2001–06/2006. Research Scientist. Dana-Farber Institute, Harvard Medical School, Boston, MA, USA

    • Topic: Molecular basis of Immune Recognition.

    • Reporting to: Prof. Ellis L. Reinherz, Chief of the laboratory of Immunobiology

  • 05/1998–02/2001. Postodoctoral Scientist at DNAX, Research Institute, Palo Alto, CA, USA.

    • Topic: Discovery and functional analysis of novel molecules.

    • Funding: Post-Doctoral Fellowship from DNAX Research Institute

    • Supervisor: Dr. Fernando J. Bazan

  • 09/1995–06/1998. Post-doctoral Scientist at Dept. of Biochemistry, University of Cambridge, UK.

    • Topic: Molecular and structural bases of the post-translational modification of biotinyl and lipoyl domains. Protein-protein interactions underlying catalysis and protein assemble in multienzyme complexes.

    • Funding: FEBS Fellowship (09/1995 – 08/1997) and BBSRC Research Associate contract (09/1997–05/1998)

    • Supervisor: Prof. Richard N. Perham

  • 09/90-06/95 PhD Student at Instituto de Parasitología y Biomedicina" (CSIC), Granada, Spain.

    • Topic: Identification and characterization of potential drug targets in Trypanosoma cruzi

    • Funding: PhD Fellowship from Junta de Andalucia, Spain

    • Supervisor: Dr. Luis Miguel Ruiz Perez & Dra. Dolores Gonzalez Pacanowska


Academic appointments

  • 07/2011-present. Associate Professor  (Immunology): Department of Microbiology I (Immunology), Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

  • 09/2012-09/2015. Coordinator of the Master in Research in Inmunology, Facultad of Medicina (School of Medicine), Universidad Complutense de Madrid, Madrid, Spain (http://www.ucm.es/info/inmuno/master.htm)

  • 04/2011-07/2011. Visiting Professor: Department of Microbiology I (Immunology), Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

  • 04/2006-04/2011. Academic and Investigator Personnel (Personal Académico e Investigador Ramón y Cajal): Department of Microbiology I (Immunology), Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain

  • 02/2001-06/2006. Instructor of Medicine. Department of Medical Oncology, Harvard Medical School, Boston, MA


Selected teaching activity

  • 2007-present. Principles of Immunology, Biochemistry, Medicine and Biology Majors, UCM, Spain (Course Director: Pedro A Reche)

  • 2010-present. Immunotechnology, Master of Immunology; School of Medicine, Universidad Complutense de Madrid (UCM), Spain (Course Director: Dr. Pedro A Reche)

  • Immunochemistry and Cellular Immunology, Biochemistry major, second cycle; School of Chemistry, UCM, Spain (Course Director: Pedro A Reche)
  • 200-2015. Immunoinformatics,  Master of Bioinformatics,  National School of Health (Course Director: Federico Morán)
  • 2006-2007. Bioinformatics Approaches in Immunology Research; Instituto Gulbenkian de Ciencia, Oeiras,  Portugal (Course Organizer: Pedro Fernandes)

  • 2003-2006. Components of Antigen Processing and Presentation, Molecular Basis of Human Disease course;   Harvard Medical School, USA (Course Director: Edmond Yunis).


Awards and Fellowships

  • 09/1995–09/1997. Post-Doctoral Fellowship, Federation of European Biochemistry Societies (FEBS)

  • 03/1994–05/1994. Short Term Pre-Doctoral Research Fellowship, European Science Exchange Program, The Royal Society, UK.

  • 03/1994–05/1994.  Short Term Pre-Doctoral Research Fellowship, Junta de Andalucía, Spain.

  • 10/1990–09/1994.  PhD Fellowship, Junta de Andalucía, España

  • 09/1988–09/1990.  Undergraduate Research Fellowship, Ministerio de Educación y Ciencia, España.


Report of selected competitive funding

  • Desarrollo asistido por computadora de vacunas de epitopos: aplicacion al Rhinovirus humano.

    • Source: Ministerio de Economía y Competividad, Spain (REF: BIO2014-54164-R)

    • From:  01/10/2015 to 30/09/2018

    • Role:  Principal Investigator

  • Development of bacterial immunopotenciator to prevent chronic pulmonary diseases.

    • Source: Ministerio de Innovación y Ciencia, Spain (REF: IPT-2012-0639-090000)

    • From:  01/01/2013 to 31/12/2015

    • Role: Co-Principal Investigator

  • Pan-individual stimulation of T cell immune response against conserved CD8 T cell epitopes from hepatitis C virus.

    • Source: Ministerio de Innovación y Ciencia, Spain (SAF2009-08103)

    • From:  01/01/2010 to 31/12/2012

    • Role: Principal Investigator

  • Computer-aided design of epitope vaccines: application to hepatitis C virus

    • Source: Comunidad Autonoma de Madrid, Spain(CCG08-UCM/BIO-3769)

    • From: 01/01/2009 to  28/02/2010

    • Role: Principal Investigator

  • Bioinformatics Resources for immunotherapy against cancer

    • Source: Ministerio de Educación y Ciencia, Spain (SAF2006-07879)

    • From:  30/09/2006 to 31/03/2010

    • Role: Principal Investigator


Patents

  • Title: Mammalian cytokines; receptors; related reagents and methods.

    • Inventors: Pedro A Reche-Gallardo, Vassili Soumelis, Yong-Jun Liu, Rene de Waal Malefyt, Bazan J. Fernando, Robert A. Kastelein

    • Patent Nº: 7569224 B2

    • Holder: Schering Corporation

  • Title: Identifying antibody that inhibits pathogenicity of infectious microorganism such as an orthopox virus using a programmed computer

    • Inventors: Pedro A. Reche and Ellis E. Reinherz

    • Application Number: US2003229454-A1; WO2004040398-A2; AU2003299469-A1; AU2003299469-A8

    • Holder: Dana-Farber Cancer Institute

  • Title: New IKBNS gene, useful for preparing a composition for treating e.g. cancer, malaria, tuberculosis, AIDS or autoimmune disease, such as rheumatoid arthritis, diabetes mellitus or multiple sclerosis

    • Inventors: Ellis L. Reinherz, Linda K. Clayton, Emma Fiorini, Pedro A. Reche, Ingo Schmitz

    • Application Number: WO2003018776-A; WO2003018776-A2; AU2002258548-A1; US2005084916-A1; AU2002258548-A8

    • Holder: Dana-Farber Cancer Institute

  • Title: New computer-assisted method of generating an immunogen by providing a pathogenesis factor (PI;) or its fragment and determining whether the produced compound is an immunogen in a mammalian host

    • Inventors : Ellis L Reinherz, Mikyung Kim, Pedro A Reche and Jia-Huai Wang.

    • Application Number: WO2003017032-A2; EP1417628-A2; AU2002326580-A1; US2005015232-A1; AU2002326580-A8

    • Holder: Dana-Farber Cancer Institute