PUBLICACIONES 2017:

An Update on P2Y13 Receptor Signalling and Function

Raquel Pérez-Sen, Rosa Gómez Villafuertes, Felipe Ortega, Javier Gualix, Esmerilda G. Delicado Y María Teresa Miras Portugal.

Adv Exp Med Biol - Protein Reviews DOI 10.1007/5584_2017_91  Springer Nature Singapore Pte Ltd. 2017

Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors

Lucía Paniagua Herranz, Juan C. Gil Redondo, Mª José Queipo, Silvia González-Ramos, Lisardo Boscá, Raquel Pérez-Sen, Mª Teresa Miras Portugal y Esmerilda G. Delicado.

Frontiers in Pharmacology published: 22 December 2017 doi: 10.3389/fphar.2017.00937

Specific Temporal Distribution and Subcellular Localization of a Functional Vesicular Nucleotide Transporter (VNUT) in Cerebellar Granule Neurons

Aida Menéndez Méndez, Juan I. Díaz Hernández, Felipe Ortega, Javier Gualix, Rosa Gómez-Villafuertes y María T. Miras-Portugal.

Frontiers in Pharmacology  published: 22 December 2017 doi: 10.3389/fphar.2017.00951

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

Rosa Gómez-Villafuertes, Lucía Paniagua-Herranz, Sergio Gascón, David de Agustín-Durán, María de la O Ferreras, Juan Carlos Gil-Redondo, María José Queipo, Aida Menendez-Mendez, Ráquel Pérez-Sen, Esmerilda G. Delicado, Javier Gualix, Marcos R. Costa, Timm Schroeder, María Teresa Miras-Portugal y Felipe Ortega.

Journal of Visualized Experiments 2017 Dec 16;(130):56291

Transient creb-mediated transcription is key in direct neuronal reprogramming

Sergio Gascón, Felipe Ortega y Magdalena Götz.

Neurogenesis (Austin)  2017 Feb 6;4(1):e1285383

Bifunctional Hydrogels Containing the Laminin Motif IKVAV Promote Neurogenesis

Aleeza Farrukh, Felipe Ortega, Wenqiang Fan, Nicolás Marichal, Julieta I. Paez, Benedikt Berninger, Aránzazu del Campo y Marcelo J. Salierno.

Stem Cell Reports  2017 Nov 14;9(5):1432-1440

Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke

Isabel Bravo Ferrer, María I. Cuartero, Juan G. Zarruk, Jesús M. Pradillo, Olivia Hurtado, Víctor G. Romera, Javier Díaz Alonso, Juan M. García Segura, Manuel Guzmán, Ignacio Lizasoain, Ismael Galve-Roperh y María A. Moro.

Stroke 2017 Jan;48(1):204-212

Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders

Alline C. Campos, Manoela V. Fogaça, Franciele F. Scarante, Sâmia R. L. Joca, Amanda J. Sales, Felipe V. Gomes, Andreza B. Sonego, Naielly S. Rodrigues, Ismael Galve-Roperh y Francisco S. Guimarães.

Frontiers in Pharmacology   published: 23 May 2017 doi: 10.3389/fphar.2017.00269

Loss of Cannabinoid CB1 Receptors Induces Cortical Migration Malformations and Increases Seizure Susceptibility

Javier Díaz-Alonso, Adán de Salas-Quiroga, Juan Paraíso-Luna, Daniel García-Rincón, Patricia P. Garcez, Maddy Parsons, Clara Andradas, Cristina Sánchez, François Guillemot, Manuel Guzmán e Ismael Galve-Roperh.

Cerebral Cortex, November 2017;27: 5303–5317

Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens

Yolanda Mateo, Kari A. Johnson, Dan P. Covey, Brady K. Atwood, Hui-Ling Wang, Shiliang Zhang, Iness Gildish, Roger Cachope, Luigi Bellocchio, Manuel Guzmán, Marisela Morales, Joseph F. Cheer y David M. Lovinger.

Neuron 2017 Dec 6;96(5):1112-1126

Upregulation of CB2 receptors in reactive astrocytes in canine degenerative myelopathy, a disease model of amyotrophic lateral sclerosis

Marı́a Fernández Trapero, Francisco Espejo Porras, Carmen Rodrı́guez Cueto, Joan R. Coates, Carmen Pérez Dı́az, Eva de Lago y Javier Fernández-Ruiz.

Disease Models & Mechanisms (2017) 10, 551-558

New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking

Giulio Ragusa, María Gómez Cañas, Paula Morales, Carmen Rodríguez-Cueto, María R. Pazos, Battistina Asproni, Elena Cichero, Paola Fossa, Gerard A. Pinna, Nadine Jagerovic, Javier Fernández-Ruiz y Gabriele Murineddu.

European Journal of Medicinal Chemistry 127 (2017) 398-412

Effects of a Sativex-Like Combination of Phytocannabinoids on Disease Progression in R6/2 Mice, an Experimental Model of Huntington’s Disease

Sara Valdeolivas, Onintza Sagredo, Mercedes Delgado, Miguel A. Pozo y Javier Fernández-Ruiz.

European Journal of Medicinal Chemistry 2017 Mar 23;18(4):684

Synthesis of a novel CB2 cannabinoid-porphyrin conjugate based on an antitumor chromenopyrazoledione

Paula Morales, Laura Moreno, Javier Fernández-Ruiz y Nadine Jagerovic.

Porphyrins Phthalocyanines 2017; 21: 67–76

Modeling Neurodegenerative Disorders for developing Cannabinoid-based Neuroprotective Therapies

Javier Fernández-Ruiz, María Gómez-Ruiz, Concepción García, Mariluz Hernández y José A. Ramos.

Methods Enzymol  2017  593:175-198

Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3

Carmen Rodríguez-Cueto, Mariluz Hernández-Gálvez, Cecilia J. Hillard, Patricia Maciel, Sara Valdeolivas, José A. Ramos, María Gómez-Ruiz y Javier Fernández-Ruiz.

Plos One 2017   Apr 27;12(4):e0176521

Noradrenaline induces CX3CL1 production and release by neurons

José L.M. Madrigal, Javier R. Caso, Borja García-Bueno, Irene L. Gutiérrez y Juan C. Leza.

Neuropharmacology 114 (2017) 146-155

Paliperidone reverts Toll-like receptor 3 signaling pathway activation and cognitive deficits in a maternal immune activation mouse model of schizophrenia

Karina S. MacDowell, Eva Munarriz-Cuezva, Javier R. Caso, José L.M. Madrigal, Arantzazu Zabala, J. Javier Meana, Borja García-Bueno y Juan C. Leza.

Neuropharmacology 116 (2017) 196-207

Differential regulation of the TLR4 signalling pathway in post-mortem prefrontal cortex and cerebellum in chronic schizophrenia: Relationship with SP transcription factors

Karina S. MacDowell, Raquel Pinacho, Juan C. Leza, Joan Costa, Belén Ramos y Borja García-Bueno.

Progress in Neuropsychopharmacology & Biological Psychiatry 79  2017  481-492

Lipopolysaccharide enters the rat brain by a lipoproteinmediated transport mechanism in physiological conditions

Alejandra Vargas-Caraveo, Aline Sayd, Sandra R. Maus, Javier R. Caso, José L. M. Madrigal, Borja García-Bueno y Juan C. Leza.

Scientific Reports 2017 Oct 13;7(1):13113

Effects of the antipsychotic paliperidone on stressinduced changes in the endocannabinoid system in rat prefrontal cortex

Karina S. MacDowell, Aline Sayd, Borja García-Bueno, Javier R. Caso, José L. Madrigal y Juan Carlos Leza.

The World Journal of Biological Psychiatry  2017 Sep;18(6):457-470

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia

Jesus M. Pradillo, Katie N. Murray, Graham A. Coutts, Ana Moraga, Fernando Oroz-Gonjar, Herve Boutin, Maria A. Moro, Ignacio Lizasoain, Nancy J. Rothwell  y Stuart M. Allan.

Brain, Behavior, and Immunity 61 (2017) 117–126

Test repositioning for functional assessment of neurological outcome after experimental stroke in mice

Macarena Hernández-Jiménez, Carolina Peña-Martínez, María del Carmen Godino, Jaime Díaz-Guzmán, María Ángeles Moro e Ignacio Lizasoain.

Plos One 2017 May 4;12(5):e0176770

Specific Features of SVZ Neurogenesis After Cortical Ischemia: a Longitudinal Study

Palma-Tortosa, A. García-Culebras, A. Moraga, O. Hurtado, A. Perez-Ruiz, V. Durán-Laforet, J. de la Parra, M. I. Cuartero, J. M. Pradillo, M. A. Moro e I. Lizasoain.

Scientific Reports 2017 Nov 27;7(1):16343

Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke

Isabel Bravo-Ferrer, María I. Cuartero, Juan G. Zarruk, Jesús M. Pradillo, Olivia Hurtado, Víctor G. Romera, Javier Díaz-Alonso, Juan M. García-Segura, Manuel Guzmán, Ignacio Lizasoain, Ismael Galve-Roperh y María A. Moro.

Stroke 2017 Jan;48(1):204-212

Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke

Alicia García-Culebras, Sara Palma-Tortosa, Ana Moraga, Isaac García-Yébenes, Violeta Durán-Laforet, Maria I. Cuartero, Juan de la Parra, Ana L. Barrios-Muñoz, Jaime Díaz-Guzmán, Jesús M. Pradillo, María A. Moro e Ignacio Lizasoain.

Stroke  2017  Jun;48(6):1695-1699

New Tacrines as Anti-Alzheimer’s Disease Agents. The (Benzo)Chromeno-PyranoTacrines

Maria Jesus Oset-Gasque y Jose Marco-Contelles.

Current Topics in Medicinal Chemistry, 2017, 17, 3349-3360

Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZderived neural precursor cells

Eduardo H. Sánchez-Mendoza, Victor Bellver-Landete, Carmen Arce, Thorsten Doeppner, Dirk M. Hermann y María Jesús Oset-Gasque.

Plos One 2017 May 11;12(5):e0177069

Effects of repeated social defeat on adolescent mice on cocaine-induced CPP and self-administration in adulthood: integrity of the blood–brain barrier

Marta Rodríguez-Arias, Sandra Montagud-Romero, Ana Rubio-Araiz, María A. Aguilar, Elena Martín-García, Roberto Cabrera, Rafael Maldonado, Francesca Porcu, María Isabel Colado y José Miñarro.

Fluorescent Probes in Medicinal Chemistry

Silvia Ortega Gutiérrez.

Biology, Chemistry  Published 14 November 2017

Disruption of blood–brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model

Ana Rubio-Araiz, Francesca Porcu, Mercedes Pérez-Hernández, Mª Salud García-Gutiérrez, María Auxiliadora Aracil-Fernández, María Dolores Gutierrez-López, Consuelo Guerri, Jorge Manzanares, Esther O’Shea y María Isabel Colado.

Addiction Biology  2017 Jul;22(4):1103-1116