Grupos de investigación

Santiago Herrero Domínguez

His scientific career began at Saragossa University and the Institute of Materials Science of Aragon (Spain), where he completed his doctoral thesis under the direction of R. Usón and M.A. Usón. The most outstanding result was the synthesis of new palladium(I) compounds and the study of their metal-metal bond that showed that the classical interpretation on the metal-metal bond was not correct for them (Inorg.Chem. 1997,36,1912). From his postdoc in Texas A&M (USA), under the supervision of F.A. Cotton, it is remarkable the definitive assignment of all visible transitions of dimolibdenum(II) compounds with quadruple metal-metal bond and the preparation of what is probably the most complete example of rotation isomers in the literature (J.Am.Chem.Soc. 1999,121,11758). Next, he worked on the functionalization of dendrimers at Centre National de la Recherche Scientifique (Bordeaux, France) with D. Astruc and Autonomous University of Madrid (Spain) with I. Cuadrado (Organometallics 2007,26,2688).

In the last period, already at the Complutense University of Madrid (UCM, Spain), he changed again the subject of research to work in molecular magnetism within the group led by R. Jiménez-Aparicio. His most relevant contribution was the synthesis of the first compound with quantum spin mixing with a non first transition series metal and whose magnetic behavior resembles cytochromes c' (Angew.Chem.Int.Ed. 2005,44,305; J.Am.Chem.Soc. 2007,129,12666). We also pioneered the use of more sustainable synthetic methods for metal clusters by using microwaves (Green Chem. 2010,12,965; Green Chem. 2011,13,1885; Microwave-assisted solvothermal synthesis of inorganic compounds, in Microwave Chemistry, G. Cravotto, D. Carnaroglio, De Gruyter, 2017) and, more recently, by using ultrasounds (Ultrason.Sonochem. 2021,80,105828. All these findings were possible using formamidinates (Coord.Chem.Rev.2019,400,213040).


In recent years, he has promoted the use of diruthenium compounds in biology, (RNA, 2016,22,330; J.Inorg.Biochem. 2018,187,109; Inorg.Chem. 2020,59,7779). The first results have been protected with a patent (Nº 201500550. Concession: 03/16/2018. UCM) as this compound is capable to detect RNA structural motifs.

From 2021, he is assumed the leadership of the UCM MatMoPol research group (https://www.ucm.es/matmopol/) and he is trying to boost the research activity of the group with the new young researchers who just joined the team.
His work has also contributed to the field of Chemical Education and scientific dissemination. We proposed a simple method to assign the chirality symbol to tris-chelate octahedral compounds, that is used in universities around the world (J.Chem.Educ. 1995,72,1065), and a formulation method for octahedral compounds with polydentate ligands that was top 10 in Dalton for months and was discussed in several journals (Dalton Trans. 2008,37,4993). He also worked as a scientific editor for the Universal Encyclopedia Micronet and he has coordinated several teaching innovation and scientific dissemination projects. He has delivered workshops in primary, secondary, and special education centers (people with intellectual disabilities, Bol.R.Soc.Esp.Hist.Nat. Sect. Classroom, Museums, Collections 2017,4,5).