Vascular reactivity


 Myography is a laboratory technique which allow us to study vascular reactivity.  To perform these experiments, we use vascular vessels ex vivo to study vasoconstriction and vasodilation against different drugs. Vessel segments are incubated in a warm bath and between two wires that go through the lumen. One of these wires is connected to a force-transducer which record the strain developed by the vessel, whereas the second wire is linked to a micrometric screw that allow us to choose the initial strain. 

Organs Bath

The organ bath allows us to study vascular responses to different drugs. By attaching the tissue/organ to a wire which is linked to a force-transducer, we can record the vasoconstriction or vasodilation of the tissue to different drugs or gas conditions