Juan Pablo Gutiérrez García

Profesor Titular

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Doctor en Veterinaria

Ingeniero Técnico en Informática de Gestión

Especialista Universitario en Mejora Genética Animal

Departamento de Producción Animal

Facultad de Veterinaria

Universidad Complutense de Madrid

Avda. Puerta de Hierro s/n

28040 Madrid

Phone and FAX: +34 91 394 3767

E-mail: gutgar@vet.ucm.es

Endog download area

Molkin download area

Papers

Link to the 5^th European Symposium on South American Camelids and First European Meeting on Fibre Animals

ENTIDAD COLABORADORA: PCE IBÉRICA

Endog 4.8: A computer program for analysing pedigree information

Primary functions carried out by ENDOG are the computation of the individual inbreeding (F) (Wright, 1931) and the average relatedness (AR) (Gutiérrez et al., 2003; Goyache et al., 2003) coefficients. Additionally, users can compute with ENDOG useful parameters in population genetics such as that described for Biochard et al. (1997) for the number of ancestors explaining genetic variability or those proposed by Robertson (1953) and Vassallo et al. (1996) for the genetic importance of the herds. ENDOG also can compute F statistics (Wright, 1978) from genealogical information following Caballero and Toro (2000; 2002). Moreover, the present version of ENDOG calculates effective population size following different methodologies including regression approaches and particularly the recently proposed realized effective population size from individual increase in inbreeding (Gutiérrez et al., 2008), modified to account for avoidance of self-fertilization (Gutiérrez et al., 2009).

Endog 4.8 User’s Guide (10 november 2010)

Endog 4.8 (English Version) (10 november 2010)

-> Download this additional file for Selfing Version (USER’S GUIDE NO UPDATED!) (28 september 2011)

Endog 4.0 (Versión en español) (15 november 2006)

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Molkin 3.0: A computer program for genetic analysis of populations using molecular coancestry information

MolKin (current version 3.0) is a population genetics computer program that conducts several genetic analyses on multilocus information in a user-friendly environment. Primary functions carried out by MolKin are the computation of the between individuals (and populations) molecular coancestry coefficients (f_ij), the Kinship distance (D_k) at individual and population levels. Additionally, users can compute with MolKin a set of among populations, genetic distances and F-statistics (Wright, 1978) from multilocus information. The current version of MolKin provides different methods to quantify contributions to diversity to set priorities for conservation. The program will help researchers or those responsible for population management to assess genetic variability and population structure at reduced costs with respect to dataset preparation.

Molkin 3.0 User’s Guide (22 may 2009)

Molkin 3.0 (22 may 2009)

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PUBLICACIONES CON ÍNDICE DE IMPACTO

PAPERS IN SCI JOURNALS

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For reprints, please e-mail me

· SANTANA JR, M.L., OLIVEIRA, P.S., ELER, J.P., FERRAZ, J.B.S., GUTIÉRREZ, J.P., (2012) Pedigree analysis and inbreeding depression on growth traits in Brazilian Marchigiana and Bonsmara breeds. Journal of Animal Science, 90: 99-108.. [PDF]

· PUN, A., GOYACHE, F., CERVANTES, I., GUTIÉRREZ, J.P., (2012) Cytoplasmic line effects for birth weight and preweaning growth traits in the Asturiana de los Valles beef cattle breed. Livestock Science,143: 177-183. [PDF]

· BARTOLOMÉ, E., CERVANTES, I., VALERA, M., GUTIÉRREZ, J.P., (2011) Influence of foreign breeds on the genetic structure of the Spanish Sport Horse population. Livestock Science, 142: 70-79. [PDF]

· LEGAZ, E., CERVANTES, I., PÉREZ-CABAL, M.A., DE LA FUENTE, L.F., MARTÍNEZ, R., GOYACHE, F., GUTIÉRREZ, J.P., (2011) Multivariate characterisation of morphological traits in Assaf (Assaf.E) sheep. Small Ruminant Research, 100: 122-130. [PDF]

· MORENO, A., SALGADO, C., PIQUERAS, P., GUTIÉRREZ, J.P., TORO, M.A., IBÁÑEZ-ESCRICHE, N., NIETO, B., (2011) Restricting inbreeding while maintaining selection response for weight gain in Mus musculus. Journal of Animal Breeding and Genetics, 128: 276-283. [PDF]

· GUTIÉRREZ, J.P., VARONA, L., PUN, A., MORANTE, R., BURGOS, A., CERVANTES, I., PÉREZ-CABAL, M.A., (2011) Genetic parameters for growth of fiber diameter in alpacas. Journal of Animal Science, 89: 2310–2315. [PDF]

· CERVANTES, I., PASTOR, J.M., GUTIÉRREZ, J.P., GOYACHE, F., MOLINA, A., (2011) Computing Effective Population Size from molecular data: The case of three rare Spanish ruminant populations. Livestock Science, 138:202-206. [PDF]

· CERVANTES, I., GOYACHE, F., MOLINA, A., VALERA, M., GUTIÉRREZ, J.P., (2011) Estimation of effective population size from the rate of coancestry in pedigreed Populations. Journal of Animal Breeding and Genetics,128: 56-63. [PDF]

· Pérez-Cabal, M.A., Cervantes, I., Morante, R., Burgos, A., Goyache, F., GUTIÉRREZ, J.P., (2010) Analysis of the existence of major genes affecting alpaca fiber traits. Journal of Animal Science, 88: 3783-3788. [PDF]

· PANETTO, J.C.C., GUTIÉRREZ, J.P., FERRAZ, J.B.S., CUNHA, D.G., GOLDEN, B.L., (2010) Assessment of inbreeding depression in a Guzerat dairy herd: effects of individual increase in inbreeding coefficients on production and reproduction. Journal of Dairy Science, 93: 4902-4912. [PDF]

· PÉREZ-PARDAL, L., ROYO, L.J., BEJA-PEREIRA, A., CHEN, S., CANTET, R:J.C., TRAORÉ, A., CURIK, I., SÖLKNER, J., BOZZI, R., FERNÁNDEZ, I., ÁLVAREZ, I., GUTIÉRREZ, J.P., GÓMEZ, E., PONCE DE LEON, F.A., GOYACHE, F. (2010) Multiple paternal origins of domestic cattle revealed by Y-specific interspersed multilocus microsatellites. Heredity, 105: 511-519. [PDF] [Supplementary information]

· BARTOLOMÉ, E., GOYACHE, F., MOLINA, A., CERVANTES. I., VALERA, M. GUTIÉRREZ, J.P. (2010) Pedigree estimation of the (sub) population contribution to the total gene diversity: the horse coat colour case. Animal, 4(6):867-875. [PDF]

· CERVANTES, I., PÉREZ-CABAL, M.A., MORANTE, R., BURGOS, A., SALGADO, C., NIETO, B., GOYACHE, F., GUTIÉRREZ, J.P. (2010) Genetic parameters and relationships between fibre and type traits in two breeds of Peruvian alpacas. Small Ruminant Research, 88:6-11. [PDF]

· CERVANTES, I., GUTIÉRREZ, J..P., FERNÁNDEZ, I., GOYACHE, F., (2010) Genetic relationships among calving ease, gestation length, and calf survival to weaning in the Asturiana de los Valles beef cattle breed. Journal of Animal Science, 88: 96-101. [PDF]

· GOYACHE, F., FERNÁNDEZ, I., ESPINOSA, M.A., PAYERAS, L., PÉREZ-PARDAL, L., GUTIÉRREZ, J.P., ROYO, L.J., ÁLVAREZ, I. (2010) Demographic and genetic analysis of the Mallorquina sheep flockbook. ITEA, 106, 3-14. [PDF]

· Álvarez, I., Gutiérrez, J..P., Royo, L. J., Fernández, I., GOYACHE, F., (2009) Quantifying diversity losses due to selection for scrapie resistance in three endangered Spanish sheep breeds using microsatellite information. Preventive Veterinary Medicine, 91: 172-178. [PDF]

· CERVANTES, I., GUTIÉRREZ, J.P., MOLINA, A., GOYACHE, F., VALERA, M., (2009) Genealogical analyses in open populations: the case of three Arab-derived Spanish horse breeds. Journal of Animal Breeding and Genetics, 126: 335-347. [PDF]

· GUTIÉRREZ, J.P., CERVANTES, I., GOYACHE, F., (2009) Improving the estimation of realised effective population sizes in farm animals. Journal of Animal Breeding and Genetics,126: 327-332. [PDF]

· CERVANTES, I., BAUMUNG, R., MOLINA, A., DRUML, T., GUTIÉRREZ, J.P., SÖELKNER, j., VALERA, M., (2009) Size and shape analysis of morphofunctional traits in the spanish arab horse. Livestock Science, 125: 43-49. [PDF]

· TRAORE, A., ÁLVAREZ, I., TAMBOURA, H.H., ROYO, L.J., KABORE, A., FERNANDEZ, I., GUTIÉRREZ, J.P., SANGARÉ, M., OUEDRAOGO-SANOU, G., TOGUYENI, A., SAWADOGO, L., GOYACHE, F., (2009) Genetic characterisation of Burkina Faso goats using microsatellite polymorphism. Livestock Science, 123: 322-328. [PDF]

· GUTIÉRREZ, J.P., GOYACHE, F., BURGOS, A., CERVANTES, I., (2009) Genetic analysis of six production traits in Peruvian alpacas. Livestock Science, 123: 193-197. [PDF]

· GÓMEZ, M.D., VALERA, M., MOLINA, A.., GUTIÉRREZ, J.P., GOYACHE, F., (2009) Assessment of inbreeding depression for body measurements in Spanish Purebred (Andalusian) horses. Livestock Science, 122: 149-155. [PDF]

· LEGAZ, E., Álvarez, I., Royo, L.J., Fernández, I., GUTIÉRREZ, J.P., GOYACHE, F., (2008) Genetic relationships between Spanish Assaf (Assaf.E) and Spanish native dairy sheep breeds. Small Ruminant Research, 80: 39-44. [PDF]

· CERVANTES, I., GOYACHE, F., MOLINA, A., VALERA, M., GUTIÉRREZ, J.P., (2008) Application of individual increase in inbreeding to estimate realised effective sizes from real pedigrees. Journal of Animal Breeding and Genetics, 125: 301-310. [PDF]

· GUTIÉRREZ, J.P., CERVANTES, I., MOLINA, VALERA, M., A., GOYACHE, F., (2008) Individual increase in inbreeding allows estimating effective sizes from pedigrees. Genetics, Selection and Evolution, 40: 359-378. [PDF] The original publication is available at http://www.gse-journal.org

· IBÁÑEZ-ESCRICHE, N., MORENO, A., NIETO, B., PIQUERAS, P., SALGADO, C., GUTIÉRREZ, J.P., (2008) Genetic parameters related to environmental variability of weight traits in a selection experiment for weight gain in mice; signs of correlated canalised response. Genetics, Selection and Evolution, 40: 279-293. [PDF] The original publication is available at http://www.gse-journal.org

· ÁLVAREZ, I., ROYO, L.J., GUTIÉRREZ, J.P., FERNÁNDEZ, I., ARRANZ, J.,J., GOYACHE, F., (2008) Relationship between genealogical and microsatellite information characterising losses of genetic variability: empirical evidence from the rare Xalda sheep breed. Livestock Science,115: 80-88. [PDF]

· DÍAZ-SAN SEGUNDO, F., SEVILLA, N., GUTIÉRREZ, J.P., BRUN, A., (2008) Altered lymphocyte homeostasis after oral prion infection in mouse. Veterinary Inmunology and Immunopathology, 122: 204-215. [PDF]

· CERVANTES, I., MOLINA, A., GOYACHE, F., GUTIÉRREZ, J.P., VALERA, M., (2008) Population history and genetic variability in the Spanish Arab Horse assessed via pedigree analysis. Livestock Science, 113: 24-33. [PDF]

· TRAORÉ, A., ROYO, L.J., ÁLVAREZ, I., FERNÁNDEZ, I, GUTIÉRREZ, J.P., RINCÓN, C., PÉREZ-PARDAL, L., GOYACHE, F., (2008). Adjacent mutations to ovine PrnP codons 136 and 171 affect performance of the diagnostic protocol based on RT-PCR coupled to fluorescence probes. ITEA, 104(2), 106-109. [PDF]

· ÁLVAREZ, I., ROYO, L.J., FERNÁNDEZ, I., GUTIÉRREZ, J.P., PÉREZ-PARDAL, L., GUERRA, V., RINCÓN, C., TRAORÉ, A., GOYACHE, F., (2008). Genetic differentiation between two geographic subpopulations of Bermeya goat. ITEA, 104(2), 290-294. [PDF]

· CERVANTES, I., GOYACHE, F., GUTIÉRREZ, J.P., (2008). Ratio between inbreeding and coancestry rates as a measure of population subdivision. Preliminary results. ITEA, 104(2), 303-307. [PDF]

· AZOR, P.J., CERVANTES, I., VALERA, M., ARRANZ, J.J., MEDINA, C., GUTIÉRREZ, J.P., GOYACHE, F., MUÑOZ, A., MOLINA, A., (2008). Preliminary assessment of population structure of Spanish Merino Breed: traditional strains situation using genealogical and molecular analysis. ITEA, 104(2), 295-302. [PDF]

· GONZÁLEZ-RECIO, O., LÓPEZ DE MATURANA, E., GUTIÉRREZ, J.P., (2007) Inbreeding depression on female fertility and calving ease in Spanish dairy cattle. Journal of Dairy Science, 90: 5744-5752. [PDF]

· ÁLVAREZ,  I., ROYO, L.J., GUTIÉRREZ, J.P., FERNÁNDEZ, I., ARRANZ, J.,J., GOYACHE, F., (2007) Genetic diversity loss due to selection for scrapie resistance in the rare Spanish Xalda sheep breed. Livestock Science, 111: 204-212. [PDF]

· GUTIÉRREZ, J.P., LEGAZ, E., GOYACHE, F., (2007) Genetic parameters affecting 180-days standardised milk yield, test-day milk yield and lactation length in Spanish Assaf (Assaf.E) dairy sheep.  Small Ruminant Research, 70: 233-238. [PDF]

· ROYO, L.J., ÁLVAREZ,  I., GUTIÉRREZ, J.P., FERNÁNDEZ, I., GOYACHE, F., (2007) Genetic variability in the endangered Asturcón pony assessed using genealogical and molecular information. Livestock Science, 107: 162-169. [PDF]

· GUTIÉRREZ, J.P., GOYACHE, F., FERNÁNDEZ, I., ÁLVAREZ,  I., ROYO, L.J., (2007) Genetic relationships among calving ease, calving interval, birth weight and weaning weight in the Asturiana de los Valles beef cattle breed. Journal of Animal Science, 85: 69-75. [PDF]

· GUTIÉRREZ, J.P., NIETO, B., PIQUERAS, P., IBÁÑEZ, N., SALGADO, C., (2006) Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice. Genetics, Selection and Evolution, 38: 445-462. [PDF]

· GUTIÉRREZ, J.P., FERNÁNDEZ, I., ALVAREZ, I., ROYO, L.J., GOYACHE, F., (2006) Sire x contemporary group interactions for birth weight and preweaning growth traits in the Asturiana de los Valles beef cattle breed.  Livestock Science, 99: 61-68. [PDF]

· GUTIÉRREZ, J.P., ROYO L.J., ÁLVAREZ, I., GOYACHE, F., (2005) Molkin v2.0: a computer program for genetic analysis of populations using molecular coancestry information. Journal of Heredity, 96: 718-721. [PDF]

· ROYO L.J., ÁLVAREZ, I., BEJA-PEREIRA, A., MOLINA, A., FERNÁNDEZ, I., JORDANA, J., GÓMEZ, E., GUTIÉRREZ, J.P., GOYACHE, F., (2005). The origins of Iberian horses assessed via mitochondrial DNA. Journal of Heredity, 96: 663-669. [PDF]

· Gutiérrez, J.P., MARMI, J., GOYACHE, F., JORDANA, J., (2005) Pedigree information reveals moderate to high levels of inbreeding and a population genetic structure in the Catalonian donkey breed. Journal of Animal Breeding and Genetics, 122: 378-386. [PDF]

· Gutiérrez, J.P., GOYACHE, F. (2005) A note on ENDOG: a computer program for analysing pedigree information. Journal of Animal Breeding and Genetics, 122: 172-176. [PDF]

· ALVAREZ I., GUTIÉRREZ, J.P., ROYO, L.J., FERNÁNDEZ, I., GOMEZ,E., ARRANZ, J.,J., GOYACHE, F., (2005) Testing the usefulness of the molecular coancestry information to assess genetic relationships on livestock using a set of Spanish sheep breeds. Journal of Animal Science, 83: 737-744. [PDF]

· VALERA, M., MOLINA, A., GUTIÉRREZ, J.P., GÓMEZ, J.,  GOYACHE, F. (2005) Pedigree analysis in the Andalusian horse: population structure, genetic variability and influence of the Carthusian strain. Livestock Production Science, 95: 57-66. [PDF]

· GOYACHE, F., GUTIÉRREZ, J.P., FERNÁNDEZ, I.,  ROYO, L.J., ÁLVAREZ,  I., GÓMEZ, E. (2005) Genetic analysis of days open in Asturiana de los Valles beef cattle breed. Livestock Production Science, 93: 283-289. [PDF]

· ALVAREZ I., ROYO, L.J., FERNÁNDEZ, I., GUTIÉRREZ, J.P., GOMEZ,E., GOYACHE, F. (2004) Genetic relationships and admixture among sheep breeds from Northern Spain assessed using microsatellites. Journal of Animal Science, 82, 2246-2252.[PDF]

· GOYACHE, F., GUTIÉRREZ, J.P., Álvarez I., FERNÁNDEZ I., ROYO L.J, GOMEZ, E. (2003) Genetic analysis of calf survival at different preweaning ages in beef cattle. Livestock Production Science, 83: 13–20. [PDF]

· Goyache F.; FERNÁNDEZ I., ROYO L.J, Álvarez I. GUTIÉRREZ, J.P. (2003) Factors affecting actual weaning weight, preweaning average daily gain and relative growth rate in Asturiana de los Valles beef cattle breed. Archives of Animal Breeding, 46: 235-244. [PDF]

· GUTIÉRREZ, J.P., ALTARRIBA, J., DÍAZ, C., QUINTANILLA, R., CAÑÓN, J. PIEDRAFITA, J. (2003) Pedigree analysis of eight Spanish beef cattle breeds. Genetics, Selection and Evolution, 35: 43-63. [PDF]

· GOYACHE, F., GUTIÉRREZ, J.P., FERNANDEZ, I., GOMEZ, E.,  ALVAREZ, I. DIEZ, J.  ROYO, L.J. (2003) Using pedigree information to monitor genetic variability of endangered populations: the Xalda sheep breed of Asturias as an example. Journal of Animal Breeding and Genetics, 120: 95-103. [PDF]

· GUTIÉRREZ, J.P., ALVAREZ, I, FERNÁNDEZ, I, ROYO, L. J, DÍEZ, J., GOYACHE, F. (2002) Genetic relationships between calving date, calving interval, age at first calving and type traits in beef cattle. Livestock Production Science, 78: 215-222. [PDF]

· GUTIÉRREZ, J.P., GOYACHE, F. (2002) Estimation of genetic parameters of type traits in Asturiana de los Valles beef cattle breed. Journal of Animal Breeding and Genetics, 119:  93-129. [PDF]

· GOYACHE, F., ROYO, L.J., ALVAREZ, I., GUTIÉRREZ, J.P. (2002) Testing a continuous variation in preweaning expression of muscular hypertrophy in beef cattle using field data. Archives of Animal Breeding, 45 (2): 139-149. [PDF]

· GOYACHE, F., GUTIÉRREZ, J.P. (2001) Heritabilities of reproductive traits in Asturiana de los Valles beef cattle breed. Archives of Animal Breeding, 44 (5): 489-496. [PDF]

· FERNANDEZ, J., MORENO, A., GUTIÉRREZ, J.P., NIETO, B., PIQUERAS, P., SALGADO, C. (1998) Direct and correlated response for litter size and litter weight at birth in the first parity in mice. Livestock Production Science. 53: 217-223. [PDF]

· DUNNER S., CHECA M.L.., GUTIÉRREZ J.P., MARTÍN J.P., CAÑÓN J. (1998) Genetic analysis and management in small populations: the Asturcon pony as an example, Genetics, Selection and Evolution, 30: 397-405. [PDF]

· Gutiérrez, J.P., Cañón, J., Goyache, F. (1997) Estimation of direct and maternal genetic parameters for preweaning traits in the Asturiana de los Valles beef cattle breed through animal and sire models. Journal of Animal Breeding and Genetics, 114, 261-266. [PDF]

· GUTIÉRREZ, J.P., CAÑON, J., RICO, M. (1994) Comparison of two models for estimation of variance components in a sample of Spanish Holstein Friesians. Journal of Animal Breeding and Genetics, 111: 169-174. [PDF]

· Cañón J., Gutiérrez, J.P., Dunner S., Goyache F., Vallejo M. (1994) Herdbook analysis of the Asturiana beef cattle breeds. Genetics, Selection and Evolution, 26: 65-75. [PDF]

· CAÑON, J., GRUAND, J., GUTIÉRREZ, J.P., OLLIVIER, L. (1992) Expérience de sélection sur la croissance du tissu maigre chez le porc, avec un dispositif de pères répétés: evolution génétique des caractères soumis à la sélection. Genetics, Selection and Evolution, 24: 449-462. [PDF]

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Enlaces/links

Félix Goyache